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Centre de Coopération Internationale en Recherche Agronomique pour le Développement (CIRAD)

 

 

BIODIVA

 

Project Name
BIODIVA (Characterization and valorisation of the domestic and wild animal biodiversity in Vietnam)

Location
Hanoi, Ha Giang, Nghe An, Ha Tinh, Dong Nai

Objectives
The goal of the BIODIVA project is to “make a stock list, characterize, preserve and valorise the remarkable genetic diversity of wild and domestic animal populations of Vietnam in order to allow all the Vietnamese private and public actors, especially the rural population living in disadvantaged areas, to answer on a long-term basis to some of the main ecological, economic and social challenges of the future.”

Expected Outcomes:

  • The promotion of the use of local resources as “reserves of species, populations, individuals or interest genes” for the improvement of animal productivity and of the products quality, the adaptability to changes, the resistance to diseases and possibly, the identification of genes or molecules of commercial interest (industrial or pharmaceutical).
  • The improvement of the life conditions of the mountain communities while protecting their traditional way of life, through the breeding of races adapted to the local environmental constraints, which would allow the diversification and the assurance of incomes linked to the animal productions.
  • The participation to durable development through the respect and protection of cultural traditions for which the domestic and wild animal is central.
  • And in an overall view, trying to make consider within the local or national preservation policies (i). the preservation of the exceptional  specific diversity of the Annamitic Cordillera as a humanity Heritage; (ii). The evolutions of the consumption habits and the demands of local, national and international markets aiming at production methods respectful of the environment; (iii). The adaptability to the consequences of the ecological and climatic changes linked to the destruction of natural resources and the global warming.

Activities:

  • Survey and characterization of the domestic animal biodiversity of the mountain ethnic groups in the Northern Vietnam Ha Giang Province.
  • Safeguard and development of the wild bovids either under threat (Gaur, Banteg) or with an exceptional or symbolic character (Saola, Kouprey) of the centre Vietnam high plateau (EA So) and the Annamitic Cordillera.
  • Development of the animal biodiversity with a high economic value (stag Sika) in two Centre Vietnamese provinces (Nghe An and He Tinh).

Partners:
NIAH, VAST, CNIST, INRA, CIRAD, MAE, FFEM
 
Beneficiaries:
All local communities in the region

Budget:
Total for 3 years = 6 millions €

Start Date:     2004
End Date:       2007

 

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GENAVIFLU

Project Name
GENAVIFLU (Genetic susceptibility to Avian Influenza in poultry)

Location
Hanoi & France (different locations)

Objectives
To improve the knowledge of the genetic factors controlling the immune response of chicken and common duck to two H5N1 variants, highly or moderately pathogenic, as well as the response to different vaccine constructions (recombinant herpesvirus or inert vaccine).

Expected Outcomes:
the finding of significant differences between genotypes for susceptibility to avian flu, and the identification of genes and genes’pathways differentially expressed following infection or vaccination.

Activities:
The study will include 16 breeds or selected lines of chickens, and 8 breeds or selected lines of ducks, chosen in France and in Vietnam, according to previous data on their disease resistance, MHC genotype and importance for poultry production. The within-breed polymorphism will be studied on 720 individuals by sequencing 4 genes chosen for their role in disease resistance (BF2 and TAP2 of MHC, Mx, Nramp1). The same 720 individuals will be challenged for infection by one or the other of the H5N1 variants. Challenges will be performed in confined facilities for 10 birds per breed or line. A first set of experiments will compare the susceptibility of all genotypes to the two H5N1 variants. Then, the mechanisms of immune response will be studied on a subset of the lines  previously tested, by a transcriptome approach and by quantitative RT-PCR, following infection by the variant with a low virulence.

Partners:
Donor:              - MESR (French Ministry of High Education and Research)
- ANR (National Agency for Research) / GENANIMAL

In Vietnam:       - CIRAD (Emvt / PCP PRISE)
- NIAH
- NIVR

In France:         - INRA (UMR Inra/Inapg GDA + UR 1282 IASP + VIM + SAGA)
- CNRS (FRE 2397)
- ENVT (UMR Envt IHAP 1225/Inra)
- AFSSA (UR Vipac)
 
Beneficiaries:

  • the commercial commodity chain of poultry producers in VN
  • the private smallholders in VN
  • the international community

Budget:
1.900.000 USD (total amount)

Start Date:     January, 2007
End Date:       December, 2008

 

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